Thursday, February 2, 2012

disassociating from sleepiness?

A novel use for Salvia?

When the pull of sleepiness is coming on, trying to get me to fall asleep at work, just one or two leaves, chewed, seems to pull me out of it. It's a strange new use I've found for it. I'd like to hear if anyone else has tried that, and if they have an explanation for why/how that can work. It's fairly clearly not a stimulant, so how does kappa-opioid stimulation cause cancel out the effect of sleepiness?

http://journals.lww.com/anesthesiology/Abstract/1995/01000/Effects_of_Opioid_Microinjections_in_the_Nucleus.19.aspx
" the kappa agonist caused no changes in sleep‐wakefulness states."

http://bja.oxfordjournals.org/content/101/4/542.full
"sleep-producing effects through agonism at the kappa-opioid"

Strange... actually, more intense amounts (smoked extract) often helps me to relax my body and nap afterwards (fall asleep while/after coming up). So it's dual effect is hard to explain.

I also have this fear/hypothesis that daily use might degrade sleep quality, but it seems unsupported by the evidence. I'm functioning regularly on 5 to 6 hours a sleep, which for me seems amazing that I don't "crash" even more than I do every day.

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